Donovanosis: what we know about this “flesh-eating” STI

Granuloma inguinale (Donovanosis) ulcer in the vagina

Donovanosis: what we know about this “flesh-eating” STI

Donovanosis is a sexually transmitted infection called “flesh-eating” infection, also known as “inguinal granuloma”.

The disease is characterized by painless genital ulcers, which can be confused with those of syphilis. However, during its terminal development it results in the destruction of internal and external tissues, with discharge of mucus and blood. The destructive nature of donovanosis also increases the risk of superinfection with other pathogenic microbes. Causative agent:  Bacteria klebsiella granulomatis.

Important information: this article is about: biology, health and anatomy of the human body. If you feel uncomfortable, please leave this page now. Thank you!

How to recognize donovanosis?

Caused by the bacteria Klebsiella granulomatis, donovanosis is characterized by nodules, which are abnormal growths on the surface of a tissue. They are painless and appear 10 to 40 days after contamination, according to MST Prevention. The disease is said to be “flesh-eating” because it infects the skin around the genitals. In fact, when the nodules burst, lesions appear mainly on the penis, the vulvar lips or the anus. The disease is spread through unprotected sex and is believed to be more likely to affect men than women.

If left untreated, the infection can spread. These can develop into ulcers which, if left untreated, can become infected, which can lead to pain and pain. unpleasant odor. It is more likely to affect males.

How to prevent this STI (Sexually Transmitted Infections)?

According to the gynecologist, certain actions can help prevent the transmission of donovanosis. “The use of contraception greatly reduces the risk of contracting the disease, it can also be treated with antibiotics”.


Antibiotic Azithromycin 1g orally, once a week, or 500mg daily until the ulcer disappears (Recommended).

Consequences of Donovanosis

The consequences on sex life

During the period when the infection is active, a condom should be used to protect the partner. This has inevitable consequences on the sex life, on the one hand because of the condom, and on the other hand because of a certain damage to the trust between the two partners, which it is necessary to know how to discuss. However, we cannot do without this approach.

Ulcer developed as a granuloma inguinale (Donovanosis) in the penis
Ulcer developed as a granuloma inguinale (Donovanosis) in the penis. Photo credit: SOA-AIDS Amsterdam / Wikimedia Commons
The anatomical consequences

In humans: chronic pain is possible, but without necessarily having anatomical lesions. Difficulties in urinating, by constriction of the urethra or pain from chronic prostatitis may persist.
In women: the main consequences are the risks of sterility or ectopic pregnancy. Salpingitis recognized and treated late can heal by narrowing the diameter of the tube, or cause adhesions, which will prevent the free circulation of the egg. Another long-term risk is cancer of the cervix which follows infection with certain types of condyloma.

Granuloma inguinale (Donovanosis) ulcer in the vagina
Granuloma inguinale (Donovanosis) ulcer in the vagina. Photo credit: SOA-AIDS Amsterdam / Wikimedia Commons
Health risks in general

Some infections can have manifestations elsewhere in the body: for example gonorrhea which is urethritis caused by gonococcus, can cause infectious arthritis. Syphilis can lead to infections of the meninges and nervous system.
AIDS is associated with multiple infections, especially of the lungs, nervous system, digestive tract, either from the virus itself or from the opportunistic conditions it has caused. The same is true of Kaposi’s syndrome due to the immune deficiency specific to the disease. It is because of this failure of the immune system that the disease is fatal if not treated.

STD – STI | List of Sexually Transmitted Diseases and Infections

Diseases | List of Diseases: dermatological, cardiovascular, respiratory, cancer, eye, genetic, infectious, mental illness, rare

Information: Cleverly Smart is not a substitute for a doctor. Always consult a doctor to treat your health condition.

Sources: PinterPandai, Washington Post, BMJ / British Association for Sexual Health and HIV, Centers for Disease Control and Prevention

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